Even as a child, Pablo had a head for business. When he grows up, he begins working with El Alguacil and is introduced to the drug his incarceration for theft, Pablo decides to enter the cocaine business by purchasing a farm to ensure drug and Gonzalo are incarcerated for drug trafficking, while Fabio is forced to accept his sister Patricia’s relationship with the planes he purchased, Pablo ships drugs to Miami, where Graciela handles distribution. Pablo gives his brother an unforgettable builds Hacienda Nápoles. The news of an extradition treaty between Colombia and the United States puts him on high search for Irma proves fruitless, and the leaders of the organization meet to discuss the extradition witnesses firsthand the influence politicians can wield, and he ponders going into politics as a means to seize of Pablo's partners object to his political ambitions. He begins his campaign for Congress, but the party's leader doesn't want any ties to Pablo and Galán see victories in the election, but Pablo is already plotting to get rid of his takes office. Rodrigo Lara is appointed secretary of justice and uses the opportunity to make a statement against drug newspaper publishes evidence linking Pablo to drug dealing. Meanwhile, Rodrigo is accused of having ties to the resigns from his seat in Congress and orders Rodrigo's assassination. The National Police take down a huge cocaine laboratory in the is murdered on Pablo's orders. Hunted by the police, Pablo is forced to go into Jiménez learns who was behind Rodrigo's assassination and searches for them all over Medellín. Pablo's mother, wife and son flee and his associates hide in Panama while the police search for them in the wake of Rodrigo's bullies and bribes several agents of the police to obtain their protection. A pilot who works for the cartel gives the DEA compromising guerrilla group takes over the Palace of Justice, leaving civilians, police officers and some of their own members are assassinated and threatened for their attempts to bring Pablo to justice. Marcos Hérber escapes the Zuluaga is assassinated. Pablo smuggles cocaine on commercial flights. The activates the extradition process for members of the discovers the colonel's informant. The Supreme Court rejects the expulsion law. Pablo learns that his mistress, Yesenia, is cartel dealers publish a statement. Meanwhile, Pablo orders Yesenia to get an assassinates the reporter investigating Crisanto, while Chili and Topo await the right time to attack the colonel's death is met with celebration back at the hacienda. Jorge is in serious danger and fears for his is murdered by Marcos. Maj. Aristides arrives at the farm with a search warrant, much to Pablo's gives the order to kill Guillermo and worries about the situation with Chili and Medellín cartel assassinates the editor of El Espectador, and Marcos celebrates the media and the nation are devastated by the cartel's latest hit. Once again, the Supreme Court rejects the extradition changes his mind and decides he wants to turn Marcos in to the police. Meanwhile, his men threaten by Pablo, Marcos becomes the first drug trafficker to be extradited to the United men free Cain and Kiko from jail using a helicopter. Pablo must leave his house to evade capture by Col. kills Correa and Hernan, the men who clashed with Gildardo. But Mauricio, one of the partners, is looking for his decides to kill Mauricio to be done with Hernan, while the Medellín cartel declares war on the Cali the Cali cartel prepares to strike, Pablo learns about the relationship between Marino and cartel worries about the possibility of Pedro being extradited to the United States. Marino plans to escape with Cali cartel goes after Pablo, but he evades them. The secretary of justice finally gets the orders against the Motoa brothers and family suffers the consequences of the Cali cartel's attack. Pablo's men kill Col. Pedregal and make an attempt on Maj. Aristides's kidnaps Andrés Pastrana, a candidate from a powerful political family. Patricia and Enelia worry about their living police free Andrés Pastrana, but the country's attorney general is kidnapped to keep pressure on the government to not accept law to ban extradition goes before Congress and is supported by Sen. Santorini, an ally of Congress rejects the proposed law to forbid extradition, Pablo decides to take revenge by having his political enemies and the Mariachi plan to murder Galán. Magistrate Garcés Bernal is assassinated under Pablo's Quintana decides to stop using his bodyguards and walk among the people to distract the enemy. Pablo and his men plot to assassinate concerned neighbor's call to the police thwarts the cartel's attempt on Galán's life. But Chili manages to pull off the tells Gonzalo that he tried to negotiate with the government but he didn't get anything, so now he plans to kill its the death of Galán in the attack ordered by Pablo, the country is in shock. The president decides to create an elite group to fight the nation mourns Galán’s death, Juan Manuel and Gloria ask César Gaviria to continue Galán’s legacy by becoming the next Espectador is targeted in a brutal attack. Medellín's cartel meets to discuss the subject of extradition and decides to go on the elite group follows Maria to Pablo's location, and a confrontation results in Fabio's death. Pablo reacts by trying to execute the family misses his birthday celebration when they're detained at a military checkpoint. Furious, Pablo plants a bomb in the DAS manages to meet with his family after a long time without seeing Cali cartel receives news about El Mariachi, thanks to a spy in his ranks. An explosion destroys the intelligence help from Naufrago, the Cali cartel can zero in on El Mexicano. Pablo is with a enraged Pablo sends his men a list of 17 people who must suffer consequences for their and the organization try to negotiate an agreement with the orders Evencio's murder. When the president suspends negotiations, Pablo unleashes a new reward for every dead police officer generates a wave of terror. Presidential candidate Bernardo Jaramillo meets his puts a $100,000 bounty on Col. Pabón's head and tells Gen. Pedraza that the paramilitaries plan to kill presidential candidate Diego Pabón learns who Chili's informant is and plans to use him as bait. The government offers a $1 million reward for Pablo's Pabón's men find Chili. A leader of the paramilitaries tells the police Pablo's and his men are relentlessly targeted by the elite group, forcing them to flee to the jungle, where Pablo contracts continues his war against the government, planting several bombs in Bogotá. César Gaviria takes office as the new president of reflects on the good times he shared with his cousin Gonzalo. The father of the Motoa brothers urges them to leave the business and Motoa brothers try to negotiate a deal with the government, but the president doesn't agree to the terms. Pablo kidnaps several public kidnaps two more people. The government agrees to new terms, and Pablo frees three journalists as a sign that he is willing to informant leads the government to some of the hostages, but Diana Turbay is caught in the crossfire. Pablo gives the order to execute a Turbay dies after a failed rescue attempt, and the country is shattered by the loss. Pablo's men hunt for the police agrees to surrender if the president meets several of his conditions, including sending Pablo to a prison in Medellín. Maruja Pachón is Santana is freed. After Pablo negotiates the terms of his surrender, he's detained in La Catedral, a Gonzales brothers look for alliances to make an attempt against Pablo. Topo takes some money that belongs to orders the assassination of Ramada and Arellano. The government learns about Pablo's activities inside the prison and sends in the elite enemies form a new organization called Los Pepes that helps the police to capture El Buitre and eliminate family tries to flee the country. Thanks to Los Pepes, the police manage to locate Topo. Candonga surrenders to the jail, Peluche receives a letter bomb that leaves him injured. Pablo says he will cooperate if his family is given protection in another family is turned away from Germany and returned to Colombia. A search squadron traces a phone call that Pablo makes to his family.